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Matthew Perry passed away

Matthew Perry passed away as a result of the immediate consequences of Ketamine, as confirmed by the findings of the autopsy.

Matthew Perry had been undergoing ketamine infusion therapy before his death, reportedly for depression and anxiety.

Friends star Matthew Perry, 54, died from the acute effects of Ketamine, according to the toxicology report from the Los Angeles County Medical Examiner’s Office. Contributing factors in Perry’s death included drowning, coronary artery disease, and the effects of buprenorphine (used to treat opioid use disorder), Variety reported.

Perry had been undergoing ketamine infusion therapy before his death, reportedly for depression and anxiety. The toxicology report stated, “At the high levels of ketamine found in his postmortem blood specimens, the main lethal effects would be from both cardiovascular overstimulation and respiratory depression.”

Ketamine molecular structure and its applications in medicine and recreational use

Ketamine is illegally used as a recreational drug for its numbing and hallucinogenic effects. “There were trace amounts of Ketamine detected in the stomach contents. He was reported to be receiving ketamine infusion therapy for depression and anxiety. Per the Medical Examiner Investigator’s report, his last known treatment was 1.5 weeks before death, and the Ketamine in his system at death could not be from that infusion therapy since Ketamine’s half-life is 3 to 4 hours or less,” the report added.

No alcohol was detected in his system by the autopsy report. Nor were there any traces of other drugs such as cocaine, heroin, or fentanyl. The examiner’s report does not specify how or when Perry had consumed the fatal dose of Ketamine.

Perry, best known for his role as Chandler Bing on the hit TV sitcom Friends, was found unconscious in his home’s hot tub on October 28. Perry’s untimely demise left his fans, family, and colleagues heartbroken.

Following his death, the Friends cast wrote about their experiences with Perry and how much his character, Chandler Bing, meant. Matt LeBlanc, who portrayed Joey Tribiani on Friends, shared a post on Instagram with a carousel of images and a heartfelt note for Perry. He wrote, “Matthew, I say goodbye with a heavy heart. The times we had together are among my life’s favourite times.”

“I am so grateful for every moment I had with you, Matty, and I miss you every day. When you work with someone as closely as I did with Matthew, there are thousands of moments I wish I could share. For now, here’s one of my favourites,” Courteney Cox wrote.

Taking to Instagram, David Schwimmer wrote, “Matty, Thank you for ten incredible years of laughter and creativity. I will never forget your impeccable comic timing and delivery. You could bend a straight line of dialogue to your will, resulting in something so entirely original and unexpectedly funny it still astonishes you. And you had heart. You were generous and shared with us so we could create a family out of six strangers.”

He also shared a picture with Matthew from one of his favourite moments on the Friends set. “This photo is from one of my favorite moments with you. Now, it makes me smile and grieve at the same time. I imagine you up there, somewhere, in the same white suit, hands in your pockets, looking around– ‘Could there be any more clouds?'” he added.

“Matty, I love you so much, and I know you are now completely at peace and out of pain. I talk to you every day… sometimes I can almost hear you saying could you BE any crazier? Rest, little brother. You always made my day..,” Jennifer Aniston posted.

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